0494 : Vascular protective effects of an amphiphilic nitrone against hyperglycemia-induced oxidative damages
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چکیده
منابع مشابه
Protective effects of rosuvastatin against hyperglycemia-induced oxidative damage in the pancreas of streptozotocin-induced diabetic rats
Introduction: According to the powerful antioxidant effects of rosuvastatin, the present study aimed to examine the protective effects of rosuvastatin against oxidative damage of diabetic pancreas by potentiation of the antioxidant capacity in streptozotocin-induced diabetic rats. Methods: Experiment was performed in four groups of male Wistar rats (n=6 in each group): normal, diabetic and ...
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متن کاملThe Natural Protective Mechanism Against Hyperglycemia in Vascular Endothelial Cells
OBJECTIVE Vascular endothelial cells (VECs) downregulate their rate of glucose uptake in response to hyperglycemia by decreasing the expression of their typical glucose transporter GLUT-1. Hitherto, we discovered critical roles for the protein calreticulin and the arachidonic acid-metabolizing enzyme 12-lipoxygenase in this autoregulatory process. The hypothesis that 4-hydroxydodeca-(2E,6Z)-die...
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ژورنال
عنوان ژورنال: Archives of Cardiovascular Diseases Supplements
سال: 2016
ISSN: 1878-6480
DOI: 10.1016/s1878-6480(16)30404-9